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I. Robert Nabi, PhD

Professor

Cellular & Physiological Sciences

The University of British Columbia

 

Talk Title

Nanoscopy powered by machine learning: novel insight into subcellular structure

earned his PhD in cancer metastasis from the Weizman Institute of Science. He is currently a professor in cellular and physiological sciences at The University of British Columbia. His research team investigates the cell biology of cancer. The expression of cellular domains, ranging from cell polarity to organelle biogenesis to membrane microdomain organization, play important roles in cell function. Dr. Nabi’s research team has elucidated the significance of various cellular domains in receptor function and cell motility. Some of their key discoveries include developing network analysis of dSTORM super-resolution microscopy to define the molecular architecture of caveolae and scaffolds and defining the role of Gp78 (also known as autocrine motility factor receptor (AMFR)), a cancer-associated receptor and E3 ubiquitin ligase in endoplasmic reticulum (ER) associated degradation, in ER-mitochondria interaction and mitophagy.