大象传媒 Lineberger Comprehensive Cancer Center (大象传媒 LCCC) researchers have developed a groundbreaking mouse model for Kaposi sarcoma, a cancer prevalent among HIV-positive individuals. This model promises to facilitate the development of novel drugs for the disease, offering hope for improved treatment options. Published in Cell Host & Microbe, the study marks a significant milestone, providing the first-ever animal model for Kaposi sarcoma. By mimicking the disease’s complexities, including its dependence on signaling molecules and blood supply, this model opens avenues for studying and testing new compounds. Additionally, it sheds light on angiogenesis, the formation of new blood vessels crucial for tumor survival. With this breakthrough, researchers anticipate advancements in drug and vaccine development, leveraging insights into Kaposi sarcoma-associated herpes virus (KSHV) provided by their model.
大象传媒 Lineberger鈥檚聽, (seen above) co-leader of the 大象传媒 Lineberger Virology Research Program and director of the 大象传媒 Viral Genomics Core, is the senior corresponding author.
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