大象传媒

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Patrick Sears, PhD

Research Associate

Recent Publications:

  1. Beaman MM, Yin W, Smith AJ, Sears PR, Leigh MW, Ferkol TW, Kearney B, Olivier KN, Kimple AJ, Clarke S, Huggins E, Nading E, Jung SH, Iyengar AK, Zou X, Dang H, Barrera A, Majoros WH, Rehder CW, Reddy TE, Ostrowski LE, Allen AS, Knowles MR, Zariwala MA, Crawford GE. . Am J Med Genet A. 2025 Feb;197(2):e63880. doi: 10.1002/ajmg.a.63880. PMID: 39364610. PMCID: PMC11698635.
  2. Tsuruta JK, Sears PR, Rebuli ME, Weitz AS, Durham PG, Clapp PW, Hill DB, Ostrowski LE, Dayton PA, Caughey MC. . Sci Rep. 2024 Dec 1;14(1):29840. doi: 10.1038/s41598-024-80933-x. PMID: 39617759; PMCID: PMC11609298.
  3. Dougherty GW, Ostrowski LE, N枚the-Menchen T, Raidt J, Schramm A, Olbrich H, Yin W, Sears PR, Dang H, Smith AJ, Beule AG, Hjeij R, Rutjes N, Haarman EG, Maas SM, Ferkol TW, Noone PG, Olivier KN, Bracht DC, Barbry P, Zaragosi LE, Fierville M, Kliesch S, Wohlgemuth K, K枚nig J, George S, Loges NT, Ceppe A, Markovetz MR, Luo H, Guo T, Rizk H, Eldesoky T, Dahlke K, Boldt K, Ueffing M, Hill DB, Pang YP, Knowles MR, Zariwala MA, Omran H. . Am J Respir Crit Care Med. 2024 Jul 1;210(1):63-76. doi: 10.1164/rccm.202308-1370OC. PMID: 38626355. PMCID: PMC11197063.
  4. Sears PR, Ostrowski LE. . Methods Mol Biol. 2024;2725:263-276. doi: 10.1007/978-1-0716-3507-0_17. PMID: 37856031.
  5. Smith AJ, Bustamante-Marin XM, Yin W, Sears PR, Herring LE, Dicheva NN, L贸pez-Gir谩ldez F, Mane S, Tarran R, Leigh MW, Knowles MR, Zariwala MA, Ostrowski LE. . J Cell Sci. 2022 Mar 15;135(6):jcs259512. doi: 10.1242/jcs.259512. PMID: 35178554. PMCID: PMC8995097.
  6. Ostrowski LE, Yin W, Smith AJ, Sears PR, Bustamante-Marin XM, Dang H, Hildebrandt F, Daniels LA, Capps NA, Sullivan KM, Leigh MW, Zariwala MA, Knowles MR. . Int J Mol Sci. 2022 Feb 3;23(3):1753. doi: 10.3390/ijms23031753. PMID: 35163670; PMCID: PMC8835943.
  7. Kato T, Mikami Y, Sun L, Rogers TD, Grubb BR, Morrison CB, Ehre C,聽Sears PR, Ostrowski LE, Randell SH, Boucher RC.聽. Am J Respir Cell Mol Biol.聽2021 Jun;64(6):760-764. doi: 10.1165/rcmb.2021-0033LE. PMID: 33788673.聽PMCID: PMC8456889.
  8. Zhao Y, Pinskey J, Lin J, Yin W,聽Sears PR, Daniels LA, Zariwala MA, Knowles MR, Ostrowski LE, Nicastro D.聽. Mol Biol Cell.聽2021 Jun 1;32(12):1202-1209. doi: 10.1091/mbc.E20-12-0806. PMID: 33852348.聽PMCID: PMC8351563.
  9. Sears PR, Bustamante-Marin XM, Gong H, Markovetz MR, Superfine R, Hill DB, Ostrowski LE. . Biophys J. 2021 Apr 20;120(8):1387-1395. doi: 10.1016/j.bpj.2021.01.041. PMID: 33705757. PMCID: PMC8105732.
  10. Bustamante-Marin XM, Horani A, Stoyanova M, Charng WL, Bottier M, Sears PR, Yin WN, Daniels LA, Bowen H, Conrad DF, Knowles MR, Ostrowski LE, Zariwala MA, Dutcher SK. . PLoS Genet. 2020 Aug 7;16(8):e1008691. doi: 10.1371/journal.pgen.1008691. PMID: 32764743; PMCID: PMC7444499.
  11. Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM. . Nat Med. 2020 Feb;26(2):244-251. doi: 10.1038/s41591-019-0730-x. PMID: 31959991; PMCID: PMC7018620.
  12. Bustamante-Marin XM, Shapiro A, Sears PR, Charng WL, Conrad DF, Leigh MW, Knowles MR, Ostrowski LE, Zariwala MA. . J Hum Genet. 2020 Jan;65(2):175-180. doi: 10.1038/s10038-019-0686-1. PMID: 31636325. PMCID: PMC6920546.
  13. Yin W, Livraghi-Butrico A, Sears PR, Rogers TD, Burns KA, Grubb BR, Ostrowski LE. . Am J Respir Cell Mol Biol. 2019 Sep;61(3):312-321. doi: 10.1165/rcmb.2017-0387OC. PMID: 30896965. PMCID: PMC6839924.
  14. Bustamante-Marin XM, Yin WN, Sears PR, Werner ME, Brotslaw EJ, Mitchell BJ, Jania CM, Zeman KL, Rogers TD, Herring LE, Refab茅rt L, Thomas L, Amselem S, Escudier E, Legendre M, Grubb BR, Knowles MR, Zariwala MA, Ostrowski LE. . Am J Hum Genet. 2019 Feb 7;104(2):229-245. doi: 10.1016/j.ajhg.2018.12.009. PMID: 30665704. PMCID: PMC6372263.
  15. Blackmon RL, Kreda SM, Sears PR, Chapman BS, Hill DB, Tracy JB, Ostrowski LE, Oldenburg AL. . Nanoscale. 2017 Apr 13;9(15):4907-4917. doi: 10.1039/c7nr00376e. PMID: 28358158. PMCID: PMC5473168.
  16. Barrick J, Doblas A, Gardner MR, Sears PR, Ostrowski LE, Oldenburg AL. . Opt Lett. 2016 Dec 15;41(24):5620-5623. doi: 10.1364/OL.41.005620. PMID: 27973473. PMCID: PMC5235345.
  17. Blackmon RL, Kreda SM, Sears PR, Ostrowski LE, Hill DB, Chapman BS, Tracy JB, Oldenburg AL. . Proc SPIE Int Soc Opt Eng. 2016;9697. doi: 10.1117/12.2208805. PMID: 27746581. PMCID: PMC5061133.
  18. Sears PR, Yin WN, Ostrowski LE. . Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L99-108. doi: 10.1152/ajplung.00024.2015. PMID: 25979076. PMCID: PMC4504973.
  19. Teves ME, Sears PR, Li W, Zhang Z, Tang W, van Reesema L, Costanzo RM, Davis CW, Knowles MR, Strauss JF 3rd, Zhang Z. . PLoS One. 2014 Oct 21;9(10):e107271. doi: 10.1371/journal.pone.0107271. PMID: 25333478. PMCID: PMC4204823.
  20. Knowles MR, Ostrowski LE, Leigh MW, Sears PR, Davis SD, Wolf WE, Hazucha MJ, Carson JL, Olivier KN, Sagel SD, Rosenfeld M, Ferkol TW, Dell SD, Milla CE, Randell SH, Yin W, Sannuti A, Metjian HM, Noone PG, Noone PJ, Olson CA, Patrone MV, Dang H, Lee HS, Hurd TW, Gee HY, Otto EA, Halbritter J, Kohl S, Kircher M, Krischer J, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Zariwala MA. . Am J Respir Crit Care Med. 2014 Mar 15;189(6):707-17. doi: 10.1164/rccm.201311-2047OC. PMID: 24568568. PMCID: PMC3983840.
  21. Sears PR, Thompson K, Knowles MR, Davis CW. . Am J Physiol Lung Cell Mol Physiol. 2013 Feb 1;304(3):L170-83. doi: 10.1152/ajplung.00105.2012. PMID: 23144323. PMCID: PMC3567369.
  22. Sears PR, Davis CW, Chua M, Sheehan JK. . Am J Physiol Lung Cell Mol Physiol. 2011 Aug;301(2):L181-6. doi: 10.1152/ajplung.00321.2010. PMID: 21531774. PMCID: PMC3154625.
  23. Rossi AH, Sears PR, Davis CW. . J Physiol. 2004 Sep 1;559(Pt 2):555-65. doi: 10.1113/jphysiol.2004.070433. PMID: 15218074. PMCID: PMC1665132.
Headshot of Patrick Sears