Dr. Graboski successfully defending her thesis, 鈥淐haracterization and Inhibition of Gut Microbial Tryptophanase and its Implications in Chronic Kidney Disease” under the guidance of Professor Matt Redinbo on September 21.
Dr. Graboski has accepted a scientist position in Boston at Scorpion Therapeutics in their Protein and Structural Sciences division. In this role she will collaborate with computational and medicinal chemists to identify druggable protein regions, make and co-crystallize these proteins, and inform drug design using structural data.
Publications
Graboski AL, Kowalewski ME, Simpson JB, Cao X, Ha M, Zhang J, Walton WG, Flaherty DP, Redinbo MR.听Cell Chem Biol. 2023 Aug 12:S2451-9456(23)00244-1. doi: 10.1016/j.chembiol.2023.07.015. Online ahead of print.听PMID:听37633277听Free article.
Simpson JB, Sekela JJ,听Graboski AL, Borlandelli VB, Bivins MM, Barker NK, Sorgen AA, Mordant AL, Johnson RL, Bhatt AP, Fodor AA, Herring LE, Overkleeft H, Lee JR, Redinbo MR.听Gut Microbes. 2022 Jan-Dec;14(1):2107289. doi: 10.1080/19490976.2022.2107289.听PMID:听35953888听Free PMC article.
听Sendi H, Yazdimamaghani M, Hu M, Sultanpuram N, Wang J, Moody AS, McCabe E, Zhang J,听Graboski A, Li L, Rojas JD, Dayton PA, Huang L, Wang AZ.听Cancer Res. 2022 Jan 1;82(1):105-113. doi: 10.1158/0008-5472.CAN-21-2269. Epub 2021 Nov 9.听PMID:听34753773听Free PMC article.
听Hewitt CS, Abutaleb NS, Elhassanny AEM, Nocentini A, Cao X, Amos DP, Youse MS, Holly KJ, Marapaka AK, An W, Kaur J, Krabill AD, Elkashif A, Elgammal Y,听Graboski AL, Supuran CT, Seleem MN, Flaherty DP.听ACS Infect Dis. 2021 Jul 9;7(7):1969-1984. doi: 10.1021/acsinfecdis.1c00055. Epub 2021 Mar 25.听PMID:听33765392听Free PMC article.
听Graboski AL, Redinbo MR.听Toxins (Basel). 2020 Sep 11;12(9):590. doi: 10.3390/toxins12090590.听PMID:听32932981听Free PMC article.听Review.
听Kaur J, Cao X, Abutaleb NS, Elkashif A,听Graboski AL, Krabill AD, AbdelKhalek AH, An W, Bhardwaj A, Seleem MN, Flaherty DP.听J Med Chem. 2020 Sep 10;63(17):9540-9562. doi: 10.1021/acs.jmedchem.0c00734. Epub 2020 Aug 11.听PMID:听32787141听Free PMC article.
Awards & Highlights
Merck/Women Chemists Committee (WCC) Research Award, 2/23/2023听– The award provides a stipend for travel expenses to the ACS Symposium in San Francisco this fall where she will present her research.
Appointed to the Pharmacological Sciences T32 from 2020-2022 and to the Kidney Center T32 from 2022-2023.
Amanda is also听an inventor on a provisional patent that was filed!
We wish you all the best, Amanda!